Description
35.1 are hybridoma cells derived from a Mus musculus B cell and myeloma. Of particular interest is their reactivity to the human T cell surface protein Tp50 (CD2), making them valuable tools for targeted research. The antibody produced by 35.1 cells inhibits T-cell proliferative responses and cytotoxicity without interfering with antibody-mediated cellular cytotoxicity. Derived from the fusion of spleen cells with NSI/1 myeloma cells, 35.1 cells express genes for immunoglobulin production, specifically monoclonal antibodies against human CD2. The isotype of the antibody is IgG2a